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PHOL 484. Translational Physiology II. 3 Units.

Physiology is the dynamic study of life, describing the vital functions of living organisms and their organs, cells, and molecules. For some clinicians, physiology is the function of an individual organ system. For others, it focuses on the cellular principles that are common to the function of all organs and tissues. Medical physiology deals with how the human body functions, which depends on how the individual organ systems function, which depends on how the component cells function, which in turn depends on the interactions among subcellular organelles and countless molecules. Translational Physiology II will explore examples of how the latest basic research in physiology and biophysics is being applied to the treatment of human disease. For example, while the students are studying the basic physiology of the urinary system, they will also be investigating how these principles are being applied to treat/cure human kidney disorders such as renal failure, high blood pressure, glomerular disease, etc.. Translational Physiology II is a lecture course (1, 2hr lecture/week, and 1, 1hr lecture/week) taught by clinical and basic science faculty. The 2 hour lecture will be given primarily by clinical faculty and is focused on applying physiological principles to clinical cases of pathophysiology. The 1 hour lecture will be given primarily by basic science faculty and will expose students to the process of translating fundamental basic science research to the clinic, that is bench-to-bedside. It is the second of a two-part course that follows topics being simultaneously covered in the Medical Physiology II course. It is divided into 4 blocks: Block 5 covers the physiology of the urinary system; Block 6 covers the gastrointestinal system and metabolism; Block 7 covers the endocrine system and reproduction, and, Block 8 covers the physiology of everyday life. Grading in the course will be based on performance on multiple choice examinations administered at the end of each block with each examination weighted according to the number of lectures contained in the block. Coreq: PHOL 482.