Biotechnology, MS
Degree: Master of Science (MS)
Field of Study: Biotechnology
The Departments of Biochemistry, Neurosciences, and Pharmacology provide an interdisciplinary home for the Master of Science in Biotechnology program. This 30 credit hour program provides classroom and research experiences that will help prepare students for various career fields across the biotech industry, from vaccine and drug development to forensics, toxicology and quality control. A key component of the program is an internship at a biotech company or a research laboratory at CWRU or an affiliated hospital. Students will select one of three specialization tracks by the end of the first semester: biochemistry, neuroscience, or pharmacology.
The Biochemistry Track gives students the broadest exposure to cutting edge experimental techniques used in the biotechnology industry and biomedical research. The track includes hands-on labs with a focus on molecular and biochemical approaches, as well as courses relevant to human health, diseases such as cancer, metabolic disorders and infectious diseases, and therapeutic development.
The Neurosciences Track is designed to introduce students to the principles of Neuroscience, including electrical and chemical communication within and between neurons, neural development, neurological diseases/disorders, as well as experimental methods commonly used in contemporary neuroscience research, including approaches to drug discovery and development.
The Pharmacology Track is designed to introduce students to the principles of pharmacology, including drug absorption, distribution, elimination, metabolism (pharmacokinetics), and drug-receptor theory and mechanism of action (pharmacodynamics), as well as contemporary approaches to drug discovery.
Applicants must have a BA, BS, or equivalent undergraduate degree in chemistry or the biological sciences. Please visit the program's website for details about the application process.
Learning Outcomes
- Students will have a critical understanding of important experimental techniques used in modern cell and molecular biology.
This material will be covered in BIOC 501. Achievement will be assessed by the grade in this course. - Students will be able to perform experiments using basic techniques in modern cell and molecular biology.
This material will be covered in BIOC 500, BIOC 502A, BIOC 502B, and BIOC 502C. Achievement will be assessed by the grades in these courses. Each of the 4 tracks uses a different subset of these courses. - Students can discuss how research is carried out in academia and the biotechnology sector, how research is funded, and how discoveries are turned into products.
This material will be covered in BIOC 511. Achievement will be assessed by the grade in this course. - Students will have significant research accomplishments from a semester-long internship either in a company or a faculty laboratory at CWRU.
Students will carry out the internship under the supervision of a research mentors and academic advisor as BIOC/NEUR/PHRM 610. Progress will reported in written and oral presentations. The grade in the course will reflect achievement.
Graduate Policies
For graduate policies and procedures, please review the School of Graduate Studies section of the General Bulletin.
Program Requirements
The Master of Science in Biotechnology prepares students for entry into the biotechnology and pharmaceutical industries. This program provides fundamental laboratory experience and builds a knowledge base that students can use to acquire advanced skills. Students can choose a track in Biochemistry, Neurosciences, or Pharmacology that offer specialized coursework and experiences. The program provides students with laboratory experience through hands-on laboratory coursework and a culminating semester-long internship in a biotech company or an academic laboratory. The MS in Biotechnology requires 30 credit hours of work and can be completed in 1.5-2 years of full-time study. It can also be completed by part-time study.
The program consists of the following elements:
- Biotechnology Core Curriculum. These courses give students a solid foundation in laboratory skills, the design and interpretation of experiments, and the practice of science.
- Tracks in Biochemistry, Neurosciences, and Pharmacology. Didactic courses in these tracks give students a solid foundation in one of these areas of biomedical science.
- Internship. Hands-on laboratory experiences in labs at CWRU or in internships at biotechnology companies will give students real-world experiences that will be valuable assets as they move into the real world after graduation.
Biotechnology Core Curriculum
Students complete the biotechnology core curriculum (7-10 credit hours) in their first year. It includes:
- BIOC 500 establishes the foundation for hands-on experience with basic laboratory skills.
- Advanced laboratory skills: BIOC 502A, BIOC 502B and BIOC 502C are in-depth lab courses in biochemistry and molecular biology. These cover techniques for the engineering, preparation, and study of proteins and nucleic acids. Techniques focusing upon eukaryotic and prokaryotic cells, and mass spectrometry are also presented. Students will take some or all these courses, depending on which track they choose.
- Experimental design: BIOC 501 introduces key techniques and how these techniques are used to answer experimental questions.
- Biotechnology practice: BIOC 511 introduces the business and practical aspects of biotechnology.
Tracks in Biochemistry, Neurosciences, and Pharmacology
The Biochemistry Track emphasizes engineering, expressing, purifying and working with proteins. The Neurosciences Track focuses on the application of biotechnology to the nervous system. The Pharmacology Track prepares students for work in the pharmaceutical industry. Finally the Research-Intensive Pharmacology Track is for students who wish to pursue a PhD in pharmacology.
The tracks offer specialized courses that give students a core of knowledge. Students also take some or all of the Biotechnology Core Curriculum, with topics selected to reflect the skills needed for research in that track. Finally, students select internships to fit their interests and areas of specialization.
Internship
The program requires an internship at a biotechnology company or in a faculty research lab at CWRU. This internship BIOC 610/NEUR 610/PHRM 610 allows students to enhance their resumés and future employment prospects with real-world experience. The internship must be completed in a laboratory and involve some benchwork. Students are expected to work at least 150 hours to accumulate 3 credit hours. Our program works with students to arrange internships.
Sample Plans of Study
Biochemistry Track Plan of Study
| First Year | ||
|---|---|---|
| Fall | Credit Hours | |
| BIOC 407 | Introduction to Biochemistry: From Molecules To Medical Science | 4 |
| BIOC 500 | Biotechnology Laboratory: Molecular Biology Basics | 1 |
| BIOC 501 | Biochemical and Cellular Techniques for Biotechnology | 3 |
| BIOC 511 | Practice and Professionalism in Biotechnology | 1 |
| Credit Hours | 9 | |
| Spring | ||
| BIOC 408 | Molecular Biology | 4 |
| BIOC 502A | Biotechnology Laboratory: Molecular Biology and Biochemical Techniques | 2 |
| BIOC 502B | Biotechnology Laboratory: Eukaryotic Molecular and Cellular Biology | 2 |
| BIOC 612 | Biochemistry Seminar II | 1 |
| Credit Hours | 9 | |
| Second Year | ||
| Fall | ||
| Approved Electives | 9 | |
| Credit Hours | 9 | |
| Spring | ||
| BIOC 610 | Internship in Experimental Biotechnology | 3 |
| Credit Hours | 3 | |
| Total Credit Hours | 30 | |
Neurosciences Track Plan of Study
| First Year | ||
|---|---|---|
| Fall | Credit Hours | |
| BIOC 500 | Biotechnology Laboratory: Molecular Biology Basics | 1 |
| BIOC 501 | Biochemical and Cellular Techniques for Biotechnology | 3 |
| BIOC 511 | Practice and Professionalism in Biotechnology | 1 |
| NEUR 401 | Biological Mechanisms of Brain Disorders | 3 |
| NEUR 415 | Neuroscience Seminars | 1 |
| Credit Hours | 9 | |
| Spring | ||
| BIOC 502B | Biotechnology Laboratory: Eukaryotic Molecular and Cellular Biology | 2 |
| NEUR 402 | Principles of Neural Science | 3 |
| NEUR 403 | Methods Neuroscience Research | 4 |
| NEUR 415 | Neuroscience Seminars | 1 |
| Credit Hours | 10 | |
| Second Year | ||
| Fall | ||
| PHRM 528 | Contemporary Approaches to Drug Discovery | 3 |
| Approved Electives | 6 | |
| Credit Hours | 9 | |
| Spring | ||
| NEUR 610 | Internship in Experimental Biotechnology | 3 |
| Credit Hours | 3 | |
| Total Credit Hours | 31 | |
Pharmacology Track Plan of Study
| First Year | ||
|---|---|---|
| Fall | Credit Hours | |
| BIOC 500 | Biotechnology Laboratory: Molecular Biology Basics | 1 |
| BIOC 501 | Biochemical and Cellular Techniques for Biotechnology | 3 |
| BIOC 511 | Practice and Professionalism in Biotechnology | 1 |
| PQHS 431 | Statistical Methods I | 3 |
| PHRM 511B | Frontiers in Pharmacology - Journal Club for MS Students | 1 |
| Credit Hours | 9 | |
| Spring | ||
| BIOC 502A | Biotechnology Laboratory: Molecular Biology and Biochemical Techniques | 2 |
| PHRM 511B | Frontiers in Pharmacology - Journal Club for MS Students | 1 |
| Approved Electives | 6 | |
| Credit Hours | 9 | |
| Second Year | ||
| Fall | ||
| PHRM 409 | Principles of Pharmacology | 3 |
| PHRM 528 | Contemporary Approaches to Drug Discovery | 3 |
| PHRM 525 | Topics in Cell and Molecular Pharmacology | 3 |
| Credit Hours | 9 | |
| Spring | ||
| PHRM 610 | Internship in Experimental Biotechnology | 3 |
| Credit Hours | 3 | |
| Total Credit Hours | 30 | |