Department of Biomedical Engineering

340 Wickenden Building
Phone: 216.368.4063; Fax: 216.368.4969
Robert F. Kirsch, Chair
bmedept@case.edu


The Department of Biomedical Engineering was established in 1968 as a joint department between the Case School of Engineering and the School of Medicine at Case Western Reserve University.  Biomedical Engineering uses engineering principles to develop innovative and unique insight into physiological mechanisms and solutions to a wide range of biomedical and clinical challenges. As one of the pioneering programs in the world, the department has established rigorous yet flexible educational programs that are emulated by many other institutions and is a national leader in cutting-edge research in several important areas. The department’s educational programs provide training in cellular and subcellular mechanisms for understanding fundamental physiological processes, in dealing with biomedical problems at the tissue and organ system level, and in integrating this knowledge in systems approaches to solving clinical problems.

Current degree programs include the BSE, MS, ME, combined BS/MS, PhD, MD/MS, and MD/PhD in Biomedical Engineering. In all of the BME programs at Case, the goal is to educate engineers who can apply engineering methods to problems involving living systems. The Case School of Engineering and the School of Medicine are in close proximity on the same campus, and all Biomedical Engineering faculty members carry joint appointments in both of these two schools, participating in the teaching, research, and decision-making committees of both. The department is also tightly linked with several major nearby medical centers (University Hospitals, Cleveland Clinic, VA Medical Center, and MetroHealth Medical Center).  Most faculty pursue research in collaboration with researchers and physicians in these institutions, and all of the Biomedical Engineering  educational programs take advantage of these close relationships.  The Biomedical Engineering department has established the Biomedical Engineering Alliance with the Department of Biomedical Engineering in the Lerner Research Institute of the Cleveland Clinic, resulting in a very large faculty cohort, research activities that are broad and deep, and strong cooperation on moving discoveries into products that improve health.

Mission 

To educate leaders who will integrate principles of both engineering and medicine to create knowledge and discoveries that advance human health and well-being. Our faculty and students play leading roles ranging from basic science discovery to the creation, clinical evolution, and commercialization of new technologies, devices, and therapies. In short, “Engineering Better Health.”

Background

Graduates in biomedical engineering are employed in industry, hospitals, research centers, government, and universities. Biomedical engineers also use their undergraduate training as a basis for careers in business, medicine, law, consulting, and other professions.

Research

Several research thrusts are available to accommodate various student backgrounds and interests. Strong research collaborations with clinical and basic science departments of the university and collaborating medical centers bring a broad range of opportunities, expertise, and perspective to student research projects.

Biomaterials/Tissue Engineering/Drug and Gene Delivery

 Fabrication and analysis of materials for implantation, including neural, orthopaedic, and cardiovascular tissue engineering, biomimetic materials, liposomal and other structures for controlled, targeted drug delivery, and biocompatible polymer surface modifications. Analysis of synthetic and biologic polymers by AFM, nanoscale structure-function relationships of biomaterials. Applications in the nervous system, the cardiovascular system, the musculoskeletal system, and cancer.

Biomedical Imaging

MRI, PET, SPECT, CT, ultrasound, acoustic elastography, optical coherence tomography, cardiac electrical potential mapping, human visual perception, image-guided intervention, contrast agents. In vivo microscopic and molecular imaging, and small animal imaging.

Biomedical Sensing

Optical sensing, electrochemical and chemical fiber-optic sensors, chemical measurements in cells and tissues, endoscopy. Wearable sensor systems analytics and machine learning algorithm development for sports health and cardiovascular applications. Internet of Things (IoT) smart sensor and smart speaker systems translational research in support of medication management, dementia, and related patient care.

Big Data Analytics and Health Informatics

Radiomics, Radiogenomics, computer-assisted diagnosis, digital pathology, co-registration, cancer detection, decision making, precision medicine, bioinformatics, image informatics, machine learning, pattern recognition, artificial intelligence, deep learning.

Neural Engineering and Neural Prostheses

Neuronal mechanisms; neural interfacing for electric and magnetic stimulation and recording; neural dynamics, ion channels, second messengers; neural prostheses for control of limb movement, bladder, bowel, and respiratory function; neuromodulation systems for movement disorders, epilepsy, pain mitigation, visceral functions; computational modeling and simulation of neural structures.

Transport and Metabolic Systems Engineering

Modeling and analysis of tissue responses to heating (e.g., tumor ablation) and of cellular metabolism related to organ and whole-body function in health (exercise) and disease (cardiac).

Biomechanical Systems

Computational musculoskeletal modeling, bone biomechanics, soft tissue mechanics, control of neuroprostheses for motor function, neuromuscular control systems, human locomotion, cardiac mechanics.

Cardiovascular Systems

Normal cardiac physiology, pathogenesis of cardiac diseases, cardiac development, therapeutic technologies, including cardiac regeneration, electrophysiological techniques, imaging technologies, mathematical modeling, gene regulation, molecular biology techniques, cardiac bioelectricity, and cardiac biomechanics.

Primary Appointments

Robert F. Kirsch, PhD
(Northwestern University)
Professor and Chair; Executive Director, Functional Electrical Stimulation Center
Restoration of movement using neuroprostheses; neuroprosthesis control system design; natural control of human movements; brain-computer interfacing; biomechanics of movement; computer-based modeling; and system identification

A. Bolu Ajiboye, PhD
(Northwestern University)
Elmer Lincoln Associate Professor; Associate Chair-Undergraduate Programs
Development and control of brain-computer-interface (BCI) technologies for restoring function to individuals with nervous system injuries

Jay Alberts, PhD
(Arizona State University)
Assistant Professor
Research into how the brain controls skilled movements and how changes in brain function affect movement performance

James M. Anderson, MD (Case Western Reserve University), PhD (Oregon State University)
Professor of Pathology, Macromolecular Science and Biomedical Engineering; Distinguished University Professor
Blood and tissue/material interactions as they relate to implantable devices and biomaterials

Suneel Apte, PhD
(Bombay University & University of Oxford)
Associate Professor
Examine how mutations in ADAMTS proteases cause birth defects that affect the heart, blood vessels, neural tube, eyes, palate and limbs

James P. Basilion, PhD
(The University of Texas)
Professor of Biomedical Engineering and Radiology
High resolution imaging of endogenous gene expression; definition of "molecular signatures" for imaging and treatment of cancer and other diseases; generating and utilizing genomic data to define informative targets; strategies for applying non-invasive imaging to drug development; and novel molecular imaging probes and paradigms

Jillian Beveridge, PhD
(University of Calgary)
Assistant Professor
Investigate joint biomechanics and injury, especially anterior cruciate ligament tear, with a combination of traditional marker-based motion capture, force data, and electromyography

Jeffrey Capadona, PhD
(Georgia Institute of Technology)
Leonard Case, Jr. Professor in Engineering; Associate Chair-Graduate Programs; Dean's Fellow for Research
Advanced materials for neural interfacing; biomimetic and bio-inspired materials; host-implant integration; anti-inflammatory materials; and novel biomaterials for surface modification of cortical neuroprostheses

Margot Damaser, PhD
(University of California at Berkeley)
Professor
Conduct regenerative medicine, tissue engineering and device development research aimed at improving the health of individuals with pelvic floor dysfunction, including urinary and fecal incontinence and pelvic organ prolapse

Kathleen Derwin, PhD
(University of Michigan)
Assistant Professor
Investigating the factors that influence clinical outcomes following rotator cuff repair, including extracellular matrix scaffold technologies to enhance healing

Colin K. Drummond, PhD (Syracuse University), MBA (Case Western Reserve University)
Professor and Assistant Chair
Medical device design; wearable sensor systems in sports health, urology and cardiology; advanced simulation for clinical decision support systems; and, clinical information systems for patient-centered care.

Dominique M. Durand, PhD
(University of Toronto, Canada)
Elmer Lincoln Lindseth Professor and Distinguished University Professor; Associate Chair-MS Program Development; Director, On-line MS Programs; Director, Neural Engineering Center
Neural engineering; neural interfacing with peripheral nervous system; electric and magnetic field interaction with neurons; neural prostheses for restoring motor function; neurophysiology and computational neuroscience of neural activity generation and propagation; neuromodulation; electrical stimulation and control of epilepsy; bioelectric medicine.

Steven J. Eppell, PhD
(Case Western Reserve University)
Associate Professor
Biomaterials; instrumentation; nanoscale structure-function analysis of orthopaedic biomaterials; and scanning probe microscopy and spectroscopy of skeletal tissues

Ahmet Erdemir, PhD
(Pennsylvania State University)
Assistant Professor
Developing state-of-the-art computational representation of the human body to determine how movement patterns and loads on the joints affect tissues and cells

David Escobar, PhD
(University of Minnesota)
Assistant Professor
Research integrates neurophysiology, feedback control engineering, signal processing, and data science to 1) characterize neural circuit dynamics underlying dysfunction in Parkinson's disease and epilepsy, and 2) advance the development of personalized neuromodulation therapies.

Stephen Fening, PhD
(Ohio University)
Professor; Managing Director, Case-Coulter Translational Research Partnership
Patient care through translational research and commercialization

Aaron Fleischman, PhD
(Case Western Reserve University)
Assistant Professor
Research into the application of micro and nano technology, including how to shrink high-functioning large systems into small computer-like chips for implantation or minimally invasive procedures

Kiyotaka Fukamachi, PhD
(Kyushu University)
Professor
Pioneering surgical and device treatments for heart failure; investigating mechanical support devices, such as implantable heart pumps, the total artificial heart, and advanced heart valves

Chaitali Ghosh, PhD
(Indian Institute of Toxicology Research & Hamdard University)
Associate Professor
Investigating novel therapeutic targets at the blood-brain barrier to improve drug efficacy, and devise strategies for early therapeutic intervention in pharmacoresistant epilepsy

Emily L. Graczyk, PhD
(Case Western Reserve University)
Assistant Professor
Cortical and peripheral neurostimulation to restore and augment human sensation; brain-computer interfacing; cognitive neuroscience; sensory neuroscience; computational modeling of neurostimulation; neuroprostheses for upper limb sensorimotor function

Linda Graham, MD
(University of Michigan)
Professor
Investigating how oxidized lipids contribute to the build-up of scar tissue and block the movement of endothelial cells into an area of injury or onto a bypass graft

Miklos Gratzl, PhD
(Technical University of Budapest, Hungary)
Associate Professor
Biomedical sensing and diagnostics in vitro and in vivo; electrochemical and optical techniques; BioMEMS for cellular transport; cancer multi-drug resistance at the single cell level; and sliver sensor for multi-analyte patient monitoring

Kenneth Gustafson, PhD
(Arizona State University)
Associate Professor
Neural engineering; neural prostheses; neurophysiology and neural control of genitourinary function; devices to restore genitourinary function; and functional neuromuscular stimulation

Vincent Hascall, PhD
(Rockefeller University)
Professor
Investigate how the sugar molecule hyaluronan forms normal and abnormal matrices that are required everywhere, from successful fertilization, to the protection and repair of tissues, to cancer development

Peter S. Hovmand, PhD, MSW
(Michigan State University)
Pamela B. Davis MD PhD Professor of Medicine
Computer modeling and simulation of multiscale nonlinear feedback systems; model equivalence; community engaged system design; implementation science; structural violence (gender based violence, structural racism)

Michael Jenkins, PhD
(Case Western Reserve University)
Associate Professor, Biomedical Engineering, Pediatrics; The Dr. Donald and Ruth Weber Goodman Professor of Innovative Cardiovascular; Director of the School of Medicine Light Microscopy Imaging Core (SOM-LMIC)
Biomedical optics; optical neuromodulation; advanced 3D microscopy including tissue clearing, light-sheet microscopy, and deep learning; functional nerve imaging; Applications ranging from heart development, pain treatment, pathology, and ocular surface diseases

Efstathios (Stathis) Karathanasis, PhD
(University of Houston)
Professor, Associate Chair School of Medicine
Fabricating multifunctional agents that facilitate diagnosing; treating and monitoring of therapies in a patient-specific manner

Vijay Krishna, PhD
(University of Florida)
Assistant Professor
Leveraging nanotechnology to design next-generation nano-engineered materials for non-invasive therapies and prevention of cancer, especially skin cancer

Vinod Labhasetwar, PhD
(Nagpur University)
Professor
Explore the use of nanotechnology, such as nanoparticles that can find their way into specific cells or tissues to treat various diseases, including cancer, stroke, and cardiovascular conditions

Shuo Li, PhD
(Concordia University)
Associate Professor
Innovating foundational machine learning to unlock the full potential of the complex and heterogeneous imaging-centered clinical data to enable innovative true clinical Artificial Intelligence (AI) applications, overcoming the current challenges in healthcare

Xiaojuan Li, PhD
(University of California at Berkeley)
Professor
Exploring and developing advanced musculoskeletal imaging techniques to be applied in a range of orthopaedic and rheumatologic disorders

Zheng-Rong Lu, PhD
(Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences)
M. Frank Rudy and Margaret Domiter Rudy Professor of Biomedical Engineering; Director, Case Center for Biomolecular Engineering
Drug delivery and molecular imaging; novel targeted imaging agents for molecular imaging; novel MRI contrast agents; image-guided therapy and drug delivery; drug delivery systems; multi-functional delivery systems for nucleic acids; non-viral gene therapy

Dan Ma, PhD
(Case Western Reserve University )
Assistant Professor
Magnetic Resonance Imaging (MRI); Magnetic Resonance Fingerprinting ; Quantitative MR; MR Acquisition and Modeling;Neuroimaging

Paul Marasco, PhD
(Vanderbilt University)
Investigating sensory integration with prosthetic devices to develop translational approaches for providing natural touch and movement feedback for artificial limbs

Edward Maytin, MD, PhD
(University of Rochester)
Associate Professor
(1) Studying wound healing to learn how the extracellular matrix can regulate inflammation and fibrosis in healing wounds; (2) Studying photodynamic therapy of skin cancers in mice and humans in order to improve therapeutic response

Debra McGivney, PhD
(Case Western Reserve University)
Assistant Professor
Magnetic resonance imaging, magnetic resonance fingerprinting, mathematical modeling, inverse problems.

Michael A. Moffitt, PhD
(Case Western Reserve University)
Associate Professor
Mechanisms and therapeutic applications of photobiomodulation; deep brain stimulation for movement disorders; low amplitude spinal cord stimulation for the treatment of chronic pain; computational modeling of neural response to electrical stimulation

George F. Muschler, MD
(Northwestern University)
Professor
Development and translation of methods for harvest, processing and quantitative characterization of human stem and progenitor populations. Translate these methods to advance automated methods for fabrication and characterization of safe and effective cellular therapy strategies and products

Ela Plow, PhD
(University of Minnesota)
Associate Professor
Neurophysiology to guide movement rehabilitation and brain stimulation interventions in patients with paralysis following Stroke and spinal cord injury

Christopher Pulliam, PhD
(Case Western Reserve University)
Assistant Professor
Functional recovery after neurological injury; Patient monitoring and impairment quantification; Clinical decision support systems; Precision rehabilitation

Andrew M. Rollins, PhD
(Case Western Reserve University)
Professor; Faculty co-director, Center for Engineering Action
Biomedical optics; biomedical optical imaging; optical coherence tomography; cardiovascular and ophthalmic applications

Carl Saab, PhD
(Brown University)
Staff, Cleveland Clinic Lerner Research Institute; Director of the Pain Science Technology and Research (STAR) Lab
Research to define the brain networks mediating pain, based on emerging scientific findings showing that pain is mediated by brain activity.

Anirban Sen Gupta, PhD
(The University of Akron)
Professor
Targeted drug delivery; targeted molecular imaging; image-guided therapy; platelet substitutes; novel polymeric biomaterials for tissue engineering scaffolds

Sam Senyo, PhD
(University of Illinois)
Assistant Professor
Cardiovascular regeneration; microenvironment; stable isotopes; biomaterials, microfabrication; and drug delivery

Andrew Shoffstall, PhD
(Case Western Reserve University)
Assistant Professor
Development of minimally invasive neural interfaces; biomaterials; drug delivery; blood-brain barrier permeability

Pallavi Tiwari, PhD
(Rutgers University)
Assistant Professor
Developing Image Analysis and Machine Learning Tools for Neuroimaging applications

Ronald J. Triolo, PhD
(Drexel University)
Professor, Orthopaedics, University Hospitals-Case Medical Center, VA Medical Center, MetroHealth Medical Center
Neural prostheses, rehabilitation engineering and restoration of lower extremity function, biomechanics of human movement quantitative analysis and control of gait, standing balance and seated posture

Dustin J. Tyler, PhD
(Case Western Reserve University)
Kent Hale Smith Professor for the Case School of Engineering II
Neuromimetic neuroprostheses; laryngeal neuroprostheses; clinical implementation of nerve electrodes; cortical neuroprostheses; minimally invasive implantation techniques; and modeling of neural stimulation and neuroprostheses

D. Geoffrey Vince, PhD
(University of Liverpool)
Professor
Developing a tool that will predict which patients are at increased risk of stroke to help physicians determine the best treatment approach

Satish Viswanath, PhD
(Rutgers University)
Assistant Professor
Medical image analysis, radiomics, and machine learning schemes for imaging data. Focused on designing unique image analytics tools that capture biologically relevant measurements and conducting cross-scale associations across imaging, pathology, and -omics. Applications explored in computer-aided diagnosis & disease characterization, decision support for treatment and targeting, as well as quantitative evaluation of response to treatment in vivo; for gastrointestinal cancers and digestive diseases.

Horst A. von Recum, PhD
(University of Utah)
Professor and Executive Vice Chair
Affinity-based delivery of small molecule drugs and biomolecules for applications in device infection, HIV, orthopedics, cardiovascular, ophthalmology and cancer; directed differentiation of stem cells for tissue engineering applications, such as endothelial cells, cardiomyocytes, motor neurons and T-cells

Matthew R. Williams, PhD
(Case Western Reserve University)
Assistant Professor
Experiential education including engineering design, programming, and fabrication; control of prosthetics and assistive technology for stroke and spinal cord injury

David L. Wilson, PhD
(Rice University)
Robert J. Herbold Professor of Biomedical Engineering
Biomedical image processing; machine/deep learning; multiple modalities including OCT, CT, MRI, microscopy, and ultrasound; applications in cardiology, ophthalmology, and cancer

Xin Yu, ScD
(Harvard-MIT)
F. Alex Nason Professor II
Development and application of magnetic resonance imaging and spectroscopy methods for understanding cardiovascular and metabolic diseases, including diabetes, stroke, and cardiomyopathy.

Maciej Zborowski, PhD
(Warsaw University)
Associate Professor
Investigating novel methods of cell separation for medical applications, including rapid screening for cancer cells in blood and isolation of blood-forming stem cells


Secondary Appointments

Ozan Akkus, PhD
(Case Western Reserve)
Professor, Mechanical Aerospace Engineering
Development of novel biomaterials that will substitute bone and soft tissues, bioinspired from the synthesis of bone such that ductile biocompatible polymer matrices are subjected to mineralization. Tendon replacement strategy involves alignment of collagen monomers by a novel electrochemical method to obtain strong bundles

Harihara Baskaran, PhD
(Pennsylvania State University)
Professor, Chemical Engineering
Biotransport, Tissue/Cell metabolism, Cell transport, Microvascular tissue engineering, Cartilage tissue engineering

Jonathan Baskin, MD
(New York University)
Associate Professor, Section Chief Otolaryngology-Head & Neck Surgery, Cleveland VA Medical Center and faculty, University Hospitals-Cleveland Medical Center
Peripheral Neuromodulation, Bioengineering of bone substitutes using nanotechnology

Martin Bocks, MD
(Wayne State University School of Medicine)
Associate Professor, Pediatrics, Division of Pediatric Cardiology
Pediatric medical device development, including bioresorbable stents, wireless implantable pressure sensors, pediatric ECMO cannula

Kath Bogie, D.Phil
(Oxford University)
Associate Professor, Orthopaedics
Primary and secondary prevention of chronic wounds through novel clinically-focused approaches. Translational clinical research includes studies to determine why some people experience a continuous cycle of pressure injuries while others remain pressure injury free, looking at both biomarkers and bioinformatics, complemented with smart technology development to address these issues.

Dennis Bourbeau, PhD
(University of Pittsburgh)
Assistant Professor, Physical Medicine and Rehabilitation, MetroHealth System
Neuroprosthetics for restoring bladder and bowel function after spinal cord injury

Arnold Caplan, PhD
(Johns Hopkins University)
Professor, Biology
Development and medical use of the technology involving the mesenchymal stem cell (MSC), now called Medicinal Signaling Cells

M. Cenk Cavusoglu, PhD
(University of California, Berkeley)
Nord Professor of Engineering in Electrical, Computer, and Systems Engineering
Robotics, systems and control theory, human-machine interfaces emphasizing medical robotics, haptics, virtual environments, surgical simulation, and bio-system modeling and simulation

John Chae, MD
(Rutgers University - New Jersey Medical School)
Professor and Chair, Physical Medicine and Rehabilitation, VP for Research and Sponsored Programs, MetroHealth System
Neuromuscular Electrical Stimulation for motor relearning and neuroprosthesis in stroke; peripheral nerve stimulation for musculoskeletal pain; stroke rehabilitation

Hillel J. Chiel, PhD
(Massachusetts Institute of Technology)
Professor, Biology
Biomechanical and neural basis of feeding behavior in the marine mollusk Aplysia californica, neuromechanical system modeling, analysis of neural network dynamics

William J. Dupps, Jr. , MD, PhD
(The Ohio State University)
Professor, Ophthalmology, Cleveland Clinic's Lerner College of Medicine
Corneal and ocular biomechanics, finite element modeling of the eye, simulation-based medicine

Agata Exner, PhD
(Case Western Reserve University)
Professor, Radiology, University Hospitals-Case Medical Center
Development of contrast agents for ultrasound molecular imaging and image-guided drug delivery.

Christopher Flask, PhD
(Case Western Reserve University)
Professor, Radiology
Develops quantitative MRI techniques for both basic science and translation imaging research in multiple diseases including cancer, neurological diseases, cystic fibrosis, and chronic kidney and liver diseases

Roger French, PhD
(Massachusetts Institute of Technology)
Professor, Materials Science and Engineering
Lifetime and degradation science, photovoltaics, OLED and LED lighting and displays, polymer degradation

Michael J. Fu, PhD
(Case Western Reserve University)
Assistant Professor, Dept. of Electrical, Computer, and Systems Engineering
Virtual environments, human-computer interfaces, and functional electrical stimulation for neurorehabilitation

Mark Griswold, PhD
(University of Wuerzburg, Germany)
Professor, Radiology, University Hospitals-Case Medical Center
Rapid magnetic resonance imaging, image reconstruction and processing and MRI hardware/instrumentation

Amit Gupta, MD
(Baba Farid University of Health Sciences, Faridkot, India)
Associate Professor, Radiology
Lung cancer, Artificial intelligence Cardiac imaging, Dual energy CT, 3D printing, Radiomics, Image coregistration

Umut A Gurkan, PhD
(Purdue University)
Warren E. Rupp Associate Professor, Mechanical and Aerospace Engineering, Orthopaedics
Micro/nano engineered systems, biosensing, clinical Microfluidics, point-of-care diagnostics, microcirculation, sickle cell disease

Alex Y. Huang, MD, PhD
(Johns Hopkins University)
Professor, Pediatrics, University Hospitals Cleveland Medical Center/UH Rainbow Babies & Children's Hospital
Tumor Immunity, immune landscape and behavior in tissue microenvironment, cellular adhesion and migration

Michael W. Keith, MD
(The Ohio State University)
Professor, Orthopaedic Surgery, MetroHealth Medical Center
Restoration of motor function in hands

Kevin L. Kilgore, PhD
(Case Western Reserve University)
Peckham & Picha Professor, Orthopaedics, MetroHealth System
Neuroprosthetics for spinal cord injury and electrical nerve conduction block.

Shanina C. Knighton, PhD, RN
(Case Western Reserve University)
Instructor
Co-instructs multidisciplinary BioDesign course, senior advisor to undergraduate and graduate biomedical engineering students, research interests in technology-based self-management interventions and wearable sensors

Kandice Kottke-Marchant, MD, PhD
(Case Western Reserve University)
Professor and Chair, Pathology, Cleveland Clinic Lerner College of Medicine (Lerner Research Institute)
Thrombosis, hemostasis and vascular disease, hypercoagulable states, bleeding disorders, endothelial cell function, atherosclerosis

Kenneth R. Laurita, PhD
(Case Western Reserve University)
Professor, Medicine, MetroHealth Medical Center
Determining mechanisms of and therapy for cardiac arrhythmias, using innovative optical and electrical technologies

Seungyup Lee, PhD
(Case Western Reserve University)
Assistant Professor, Department of Medicine (Cardiology)
Cardiac Electrophysiology, Mechanism of Atrial Fibrillation, and Developing Therapeutic Approaches Using Algorithms, Devices, and Neuromodulation for Atrial Fibrillation

Zhenghong Lee, PhD
(Case Western Reserve University)
Professor, Radiology, University Hospitals Cleveland Medical Center
Quantitative PET and SPECT imaging, molecular and cellular imaging of cancer, metabolism, infectious diseases and cell-based therapies

Andrei Maiseyeu, PhD
(M. V. Lomonosov Moscow State University, Russia)
Assistant Professor, Medicine
Cardiovascular drug development and delivery, immunometabolism, mechanisms of metabolic disease, imaging of atherosclerosis, MRI contract agents, controlled release nanomaterials, microfluidics

Mehran Mehregany, PhD
(Massachusetts Institute of Technology)
Professor, Electrical Engineering & Computer Science
Micro/nano-electromechanical systems, silicon carbide semiconductor technology and microsystems, wireless health

Pedram Mohseni, PhD
(University of Michigan)
Goodrich Professor of Mechanical & Aerospace Engineering
Biomicrosystems, microelectronics for neurotechnology, wireless integrated sensing/actuating systems, point-of-care diagnostic platforms for personalized health

Raymond F. Muzic, Jr., PhD
(Case Western Reserve University)
Professor, Radiology, University Hospitals-Case Medical Center
Quantitative analysis of biomedical imaging data, physiologic modeling, optimal experiment design, assessment of new radiopharmaceuticals, imaging response to therapy, radiation oncology applications of imaging, and artificial intelligence

Tarun Podder, PhD
(University of Hawaii)
Professor, Radiation Oncology
Medical robotics; medical device design; system dynamics and control; image-guided radiotherapy; stereotactic body radiotherapy; brachytherapy; image-guided surgical intervention; application of AI in radiation therapy

Julie Renner, PhD
(Purdue University)
Assistant Professor, Chemical Engineering
Development of protein engineered materials for use in and study of electrochemical systems

Steve Schomisch, PhD
(Cleveland State University)
Assistant Professore, Surgery
Minimally Invasive Surgical Innovation

Aasef G. Shaikh, MD (Maharaja Sayajirao University), PhD (Wayne State University)
Associate Professor, Penni and Stephen Weinberg Chair in Brain Health and Vice Chair for Research, Department of Neurology, University Hospitals and Case Western Reserve University
Balance and Visuo-spatial navigation, Visual canning patterns, Cerebellar disorders, Deep Brain Stimulation for Parkinson's Disease, tremor and dystonia

Dawn Taylor, PhD
(Arizona State University)
Associate Professor, Molecular Medicine, Cleveland Clinic Lerner College of Medicine (Lerner Research Institute)
Brain-controlled neuroprosthetics; Deep brain stimulation for Parkinson's disease; Neural signal processing

Jeffrey Ustin, MD
(Stanford University School of Medicine)
Assistant Professor, General Surgery, University Hospitals
Synthetic platelet technology, robot assisted atrial fibrillation ablation, endotracheal tube technology

Russell Wang, DDS, MSD
(Indiana University)
Professor, Comprehensive Care, School of Dental Medicine
Dental implant design, instrumentation, bone regeneration, 3D printing of biomaterials, biomechanics of bone fracture, biomaterials for maxillofacial reconstruction

Gary Wnek, PhD
(University of Massachusetts, Amherst)
Professor and Chair, Macromolecular Science and Engineering
Bio-mimicking macromolecular constructs with attention to the design and irritable systems; Artificial cells; Advanced films and smart packaging systems; New approaches to impart fire resistance to common polymers

Xiong (Bill) Yu, PhD, P.E.
(Purdue University)
Professor, Civil Engineering
Smart infrastructure for healthy built-Environment, sensors and non-invasive testing, smart multifunctional materials, 3D printing, data-driven decisions, machine learning

Nicholas P. Ziats, PhD
(Case Western Reserve University)
Professor, Pathology, Biomedical Engineering & Anatomy
Biomaterials and Biocompatibility, Biomaterial Implant Retrieval and Analysis, Cardiovascular Disease and Devices, Vascular Biology

Christian Zorman, PhD
(Case Western Reserve University)
Leonard Case Jr Professor of Mechanical Aerospace Engineering, Electrical, Computer, and Systems Engineering
Development of enabling materials and processing techniques for micro- and nanosystems


Research Appointments

Musa L. Audu, PhD
(Case Western Reserve University)
Research Professor
Human musculoskeletal modeling and development of control systems for rehabilitation of individuals with spinal cord injury and other balance disorders, design of rehabilitation devices for physically challenged individuals

Hamid Charkhkar, PhD
(George Mason University)
Research Assistant Professor
Neuroprostheses to restore sensorimotor function in people with limb loss or neuromusculoskeletal impairment; Sensory-enabled assistive devices to improve balance; Translational Neuroengineering

Juhwan Lee, PhD
(Dongguk University, South Korea)
Research Assistant Professor
Development of AI methods for the quantitative, comprehensive evaluation of coronary artery disease using intravascular imaging and computed tomography

Grant A. McCallum, PhD
(Case Western Reserve University)
Research Assistant Professor
Neural engineering; neural interfacing; neuromodulation; neurophysiology, application specific integrated circuits (ASICs) and wireless implantable systems

Xinning Wang, PhD
(The Chinese University of Hong Kong)
Research Assistant Professor
Development of novel molecular image probes for the diagnosis of cancer, development of molecular cancer therapeutic approaches

Mei Zhang, PhD
(Wuhan University)
Research Scientist, School of Medicine
Nanotechnology for cancer diagnosis and treatment, imaging and manipulation of tumor microenvironment, cancer immunotherapy, adoptive T-cell immunotherapy


Adjunct Faculty

Eben Alsberg, PhD
(University of Michigan)
Adjunct Professor (University of Illinois, Chicago)
Innovative biomaterials, microenvironments and bioactive factor delivery vehicles for functional tissue engineering, regenerative medicine and disease therapeutics; control of stem cell fate decision; precise temporal and spatial presentation of signals to regulate cell function; mechanotransduction and the influence of mechanics on cell behavior and tissue formation; organoids and organogenesis; therapeutic angiogenesis; and cell-cell interactions

Kenneth B. Baker, PhD
(University of Arizona)
Adjunct Assistant Professor (Lerner Research Institute, Cleveland Clinic)
Neuromodulation, Deep Brain Stimulation, Neurophysiology, Neural plasticity, Stroke, Parkinson’s disease

Niloy Bhadra, MD, PhD
(Case Western Reserve University)
Associate Professor (PM&R, MetroHealth Medical Center)
Experimental and computational studies of high frequency waveforms for reversible conduction block of peripheral nerves, design, testing and implementation of neuroprosthetic systems for the upper limb

Michael Bruckman, PhD
(University of South Carolina)
Adjunct Assistant Professor (Haima Therapeutics LLC)
Instructor for Masters of Engineering and Management (MEM) program

Scott Bruder, MD, PhD
(Case Western Reserve University)
Adjunct Professor
Product Development and Regulatory Affairs in Regenerative Medicine, and Advising Students Regarding Careers in Industry

Richard C. Burgess, MD, PhD
(Case Western Reserve University)
Adjunct Professor (Neurological Computing, Cleveland Clinic)
Magnetoencephalography, electrophysiological monitoring, EEG processing, medical informatics

Andrew Cornwell, PhD
(Case Western Reserve University)
Adjunct Assistant Professor
Education and training for faculty, staff, and students of commercializing research technology through startups or licensing

Isabelle Deschenes, PhD
(Laval University)
Professor (Chair, Department of Physiology and Cell Biology, The Ohio State University)
Molecular mechanisms of cardiac arrhythmias, ion channels structure-function, transcriptional regulation of ion channels

Evon Ereifej, PhD
(Wayne State University)
Adjunct Professor (University of Michigan)
Improved integration of cortical prosthesis and brain tissue; nano-architecture approaches for neural interfacing, understanding of neuroinflammatory mechanisms and advanced mitigation strategies

Hossein Ghassemi, PhD
(McGill University)
Adjunct Assistant Professor
Organic Polymer Chemistry of high performance polymers, composites and adhesives. Novel materials for batteries and fuel cells. Bio-based polymers from renewable sources

Vikas Gulani, MD, PhD
(University of Illinois)
Adjunct Professor (University of Michigan)
Diffusion tensor imaging and diffusion anisotropy, MRI microscopy, body MRI, and functional MRI

Elizabeth C. Hardin, PhD
(University of Massachusetts)
Adjunct Assistant Professor (Louis Stokes VA Medical Center)
Gait mechanics and performance in health and disability, virtual reality, rehabilitation, prosthetics and orthotics, neural prostheses, modeling and simulation

Thomas Hering, PhD
(Case Western Reserve University)
Adjunct Associate Professor
Cartilage biochemistry and molecular biology, alternative mRNA splicing, proteoglycans and neurotrauma

Allison Hess-Dunning, PhD
(Case Western Reserve University)
Adjunct Assistant Professor (Louis Stokes VA Medical Center)
Micro- and nano-fabrication strategies for developing advanced neural interfaces aimed at long-term functionality

Joseph Jankowski, PhD, MBA
(Case Western Reserve University)
Adjunct Professor (Case Western Reserve University Chief Innovation Officer)
Administration of multi-party translation and commercialization programs, intellectual property management, technology-based opportunity assessment, commercialization

Fehmida Kapadia, PhD
(The Ohio State University)
Adjunct Assistant Professor
Teaching innovation and commercialization, strategy and business development

Nicola Lai, PhD
(University of Pisa, Italy)
Adjunct Associate Professor (University of Cagliari)
Quantitative understanding of regulation of energy transfer and metabolism

Mary Laughlin, MD
(State University of New York)
Adjunct Professor (Cleveland Cord Blood Center)
Development of monocytes, hematopoietic stem cells

Yajuan Li, PhD
(University of Rhode Island)
Adjunct Assistant Professor (Molecular Theranostics, LLC)
Research, development and commercialization of peptide-based pharmaceutical imaging drugs and therapeutics, regulatory affairs, formulation development.

John McDaniel, PhD
(University of Utah)
Adjunct Associate Professor (Kent State University)
Vascular health and blood flow regulation in individuals with spinal cord injuries

Matthew Moorman, (Colonel), MD, MBA
(Ohio State University)
Adjunct Assistant Professor (Clinical Associate Professor of Surgery, Clinical Assistant Professor, Medical Sciences, Case Western Reserve University School of Medicine)
Trauma resuscitation, emergency surgery, and critical care, focusing on implementing quality, safety, and high-reliability health care behaviors in the early years of medical training. Special interest in high-fidelity, simulation-based medical education.

Aaron S. Nelson, MD
(Medical College of Ohio)
Adjunct Assistant Professor, Chief Medical Officer, MIM Software Inc.
Multimodality and quantitative imaging for neurologic and cardiac disorders, oncology and radiation oncology

Leena Palomo, DDS, MSD
(NYU College of Dentistry)
Adjunct Professor (Professor & Chair, Ashman Dept of Periodontology and Implant Dentistry
Bone -prosthesis interface, wound healing in complex systemic conditions

Marc Penn, MD, PhD, FACC
(Case Western Reserve University)
Adjunct Professor (Director of Research, Summa Cardiovascular Institute, Summa Health System)
Strategies for cardiovascular cell therapy to treat cardiac dysfunction

Suguna Rachakonda, PhD, MBA
(University of Hyderabad)
Adjunct Assistant Professor, Cleveland Global Cardiovascular Innovation Center
Consultation on technology commercialization

Akhil Saklecha, MD, MBA
(Northeastern Ohio University of Medicine)
Adjunct Professor
Consultation in technology commercialization, teaching, student mentoring, faculty collaboration

Todd Ritzman, MD
(The Ohio State University)
Adjunct Associate Professor
Pediatric orthopaedic surgery

Ahlam Salameh, PhD
(Case Western Reserve University)
Adjunct Assistant Professor (FES Center, Louis Stokes Cleveland VA Medical Center)
Corticomuscular coherence, intermuscular coherence, muscle co-contraction, joint movement coordination

Nicole Seiberlich, PhD
(Universitat Wurzburg, Germany)
Adjunct Associate Professor (Radiology, University of Michigan)
Quantitative MRI, image reconstruction, pulse sequence development, cardiac imaging

Robert T. Ssekitoleko, EngD
(University of Strathclyde, Glasgow)
Adjunct Assistant Professor (Lecturer and Biomedical Engineering Program Lead in College of Health Sciences at Makerere University)
Advisor to the student design teams in the CWRU Global Health Design Collaborative. Hosts CWRU's study abroad course in Uganda, Global Health Design

Animesh (Aashoo) Tandon, MD, MS
(University of Michigan Medical School)
Adjunct Assistant Professor (Cleveland Clinic Foundation)
Wearable physiological biosensors; wearables; cardiovascular MRI for congenital heart disease; artificial intelligence; multimodal patient phenotyping; virtual and augmented reality

Antonie van den Bogert, PhD
(University of Utrecht)
Adjunct Associate Professor (Cleveland State University)
Biomechanics, Mechanics, and control of human motion

Tina Vrabec, PhD
(Case Western Reserve University)
Adjunct Assistant Professor (Physical Medicine and Rehabilitation, MetroHealt Medical Centerh)
Novel waveforms, electrode designs, and electrode materials for control of the nervous system as applied to motor block, pain, and the autonomic system

Zhong Irene Wang, PhD
(Case Western Reserve University)
Adjunct Associate Professor (Cleveland Clinic Foundation)
Epilepsy imaging (3T and 7T, MR fingerprinting), MRI post-processing (voxel-based and surface-based methods), multimodal integration for pre-surgical evaluation, magnetic source imaging

Sean Zuckerman, PhD
(University of Wisconsin-Madison)
Adjunct Instructor
Teaching, mentoring students, early stage commercialization and product development

Fredy R. Zypman, PhD
(Case Western Reserve University)
Adjunct Professor (Professor and Chairman, Department of Physics, Yeshiva University, New York)
Theoretical and computational applied physics, reconstruction of forces at the nanoscale from experimental atomic force microscopy measurements, and applications to electric and mechanical phenomena in soft matter including interactions in electrolytes; friction at the nanoscale; random systems


Emeritus Faculty

Patrick E. Crago, PhD
(Case Western Reserve University)
Professor Emeritus
Control of neuroprostheses for restoration of motor function; neuromechanics; and modeling of neuromusculoskeletal systems

J. Thomas Mortimer, PhD
(Case Western Reserve University)
Professor Emeritus
Applied neural control and neural prostheses; electrical activation of neural tissue; and electron transfer processes occurring on neural stimulation electrodes

P. Hunter Peckham, PhD
(Case Western Reserve University)
Distinguished University Professor Emeritus, Donnell Institute Professor Emeritus, and Professor Emeritus, Department of Biomedical Engineering
Rehabilitation engineering in spinal cord injury; neural prostheses; and functional electrical stimulation and technology transfer

Gerald M. Saidel, PhD
(The Johns Hopkins University)
Professor Emeritus of Biomedical Engineering
Mass and heat transport and metabolism in cells, tissues, and organ systems; mathematical modeling and simulation of dynamic and spatially distributed systems; optimal nonlinear parameter estimation and design of experiments

W. Sanford Topham, PhD
(University of Utah)
Associate Professor Emeritus
Cardiovascular system, primarily on the control of cardiac output