Department of Chemical and Biomolecular Engineering

116 A.W. Smith Building (7217)
http://engineering.case.edu/eche/
Phone: 216.368.4182
Daniel Lacks, Professor and Chair
daniel.lacks@case.edu

The Department of Chemical and Biomolecular Engineering offers Bachelor of Science in Engineering, Master of Science, and Doctor of Philosophy degree programs. The department has twelve full-time faculty members, all of whom lead active research programs in advanced and emerging areas of chemical and biomolecular engineering.

Mission

The Department of Chemical and Biomolecular Engineering inspires learning and the pursuit of scholarly activities in chemical and biological engineering and related science and engineering disciplines. The Department offers educational programs and a research environment that enable our graduates to succeed in an evolving workplace, provides opportunities for students and faculty to advance knowledge at the highest levels of the profession, and addresses technological and personnel needs of industry, governments, and society.

Background

The profession of chemical engineering involves the analysis, design, operation, and control of processes that convert matter and energy to more useful forms, encompassing processes at all scales from the molecular to the megascale. Traditionally, chemical engineers are responsible for the production of basic chemicals, plastics, and fibers. However, today’s chemical engineers are also involved in food and fertilizer production, synthesis of electronic materials, waste recycling, and power generation. Chemical engineers also develop new materials (ceramic composites and electronic chips, for example) as well as biochemicals and pharmaceuticals. The breadth of training in engineering and the sciences gives chemical engineers a particularly wide spectrum of career opportunities. Chemical engineers work in the chemical and materials-related industries, in government, and are accepted by graduate schools in engineering, chemistry, medicine, and law.

Research

Research in the department is sponsored by a variety of state and federal agencies, by private industry, and by foundations. Current active research topics include:

Energy

  • Novel energy storage systems for transportation, grid storage applications, and portable devices
  • Energy efficient extraction and processing of materials
  • Fuel cells and batteries
  • Novel catalysts, electrocatalysts, and plasmas for conversion of gases to fuels
  • Simulation, modeling, and fundamental characterization of transport and interfacial processes in electrochemical energy storage and conversion systems

Materials

  • Advanced materials for electronic and electrochemical device applications
  • Novel synthesis and deposition methods and reactor designs, including electrochemical and plasma reactors
  • Novel characterization of materials and in situ reactor diagnostics
  • Simulation and theory of materials properties
  • Surface properties and interfacial phenomena
  • Materials processing and engineering at molecular through macro scales
  • Novel separations processes

Biomolecular Engineering

  • Biosensors
  • Cell and tissue engineering
  • Biocatalysis and protein engineering

Faculty

Daniel Lacks, PhD
(Harvard University)
C. Benson Branch Professor of Chemical Engineering, Department Chair
Molecular simulation, statistical mechanics, triboelectric charging

Rohan N. Akolkar, PhD
(Case Western Reserve University)
F. Alex Nason Professor
Electrochemical phenomena in next-generation batteries, photovoltaics and semiconductor devices

Harihara Baskaran, PhD
(The Pennsylvania State University)
Professor
Transport phenomena in biology and medicine

Christine Duval, PhD
(Clemson University)
Assistant Professor
Membranes, radiochemical separations

Donald L. Feke, PhD
(Princeton University)
Distinguished University Professor and Vice Provost for Undergraduate Education
Colloidal and transport phenomena, dispersive mixing, particle science and processing

Burcu Gurkan, PhD
(University of Notre Dame)
Assistant Professor
Energy storage, nonflammable electrolytes, electrode fabrication, electrochemical separation processes

Uziel Landau, PhD
(University of California, Berkeley)
Professor
Electrochemical engineering, modeling of electrochemical systems, electrodeposition, batteries, fuel cells, electrolyzers, corrosion

Chung-Chiun Liu, PhD
(Case Institute of Technology)
Distinguished University Professor and Wallace R. Persons Professor of Sensor Technology and Control
Electrochemical sensors, electrochemical synthesis, electrochemistry related to electronic materials

Heidi B. Martin, PhD
(Case Western Reserve University)
Associate Professor
Conductive diamond films; electrochemical sensors; chemical modification of surfaces for electrochemical and biomedical applications; biomaterials; microfabrication of sensors and devices

Julie Renner, PhD
(Purdue University)
Assistant Professor
Electrochemical engineering, protein engineering, biomimetic materials, regenerative medicine

Robert F. Savinell, PhD
(University of Pittsburgh)
Distinguished University Professor and George S. Dively Professor
Electrochemical engineering, electrochemical reactor design and simulation, electrode processes, batteries and fuel cells

Jesse S. Wainright, PhD
(Case Western Reserve University)
Research Professor
Electrochemical power sources: fuel cells, batteries, supercapacitors; biomedical applications

Christopher Wirth, PhD
(Carnegie Mellon)
Assistant Professor
Colloids, multiphase materials


Emeritus Faculty

John C. Angus, PhD
(University of Michigan)
Emeritus Professor

J. Adin Mann Jr., PhD
(Iowa State University)
Emeritus Professor

Syed Qutubuddin, PhD
(Carnegie Mellon University)
Emeritus Professor

Undergraduate Programs

The Bachelor of Science in Engineering degree program with a major in Chemical Engineering is accredited by the Engineering Accreditation Commission of ABET, http://www.abet.org.

Program Educational Objectives

The undergraduate program in chemical engineering seeks to produce graduates who will:

  1. be able to excel in professional careers across a broad range of industries
  2. apply the knowledge, skills and ethical practice acquired through the chemical engineering curriculum to positively contribute to their profession and society
  3. assume positions of responsibility and/or leadership in academia, industry, government, and business
  4. succeed in post-graduate and professional degree programs

Student Outcomes

In preparation for achieving the above educational objectives, the Bachelor of Science in Engineering degree program with a major in Chemical Engineering is designed so that students attain:

  • an ability to identify, formulate, and solve complex engineering problems by applying principles of engineering, science, and mathematics
  • an ability to apply engineering design to produce solutions that meet specified needs with consideration of public health, safety, and welfare, as well as global, cultural, social, environmental, and economic factors
  • an ability to communicate effectively with a range of audiences
  • an ability to recognize ethical and professional responsibilities in engineering situations and make informed judgments, which must consider the impact of engineering solutions in global, economic, environmental, and societal contexts
  • an ability to function effectively on a team whose members together provide leadership, create a collaborative and inclusive environment, establish goals, plan tasks, and meet objectives
  • an ability to develop and conduct appropriate experimentation, analyze and interpret data, and use engineering judgment to draw conclusions
  • an ability to acquire and apply new knowledge as needed, using appropriate learning strategies.

Bachelor of Science in Engineering

Required Courses: Major in Chemical Engineering

These requirements are for students who matriculated in Fall 2020.  Students who matriculated in Fall 2019 may choose to opt into these requirements.  Students who matriculated prior to Fall 2019 can find their requirements in the General Bulletin for the year they matriculated. Note that ECHE 361, ECHE 364 and ECHE 398 are 3-credit courses before 2022, and become 4-credit courses in 2022 and thereafter.

In addition to engineering general education requirements and university general education requirements, the major requires the following courses:

Major Required Courses
ECHE 151Introduction to Chemical Engineering at Case1
ECHE 260Introduction to Chemical Systems3
ECHE 360Transport Phenomena for Chemical Systems4
ECHE 361Separation Processes4
ECHE 362Chemical Engineering Laboratory4
ECHE 363Thermodynamics of Chemical Systems4
ECHE 364Chemical Reaction Processes4
ECHE 365Measurements Laboratory3
ECHE 367Process Control4
ECHE 398Process Analysis, Design and Safety4
ECHE 399Chemical Engineering Design Project3
Related Required Courses
CHEM 223Introductory Organic Chemistry I3
or CHEM 323 Organic Chemistry I
CHEM 290Chemical Laboratory Methods for Engineers3
or all of the following three courses
Principles of Chemistry Laboratory
Introductory Organic Chemistry Laboratory I
Introductory Organic Chemistry Laboratory II
STAT 313Statistics for Experimenters3
or STAT 312 Basic Statistics for Engineering and Science
Science/Engineering Elective: One of the following courses:3
Introduction to Modern Physics
Introductory Organic Chemistry II
Introduction to Polymer Science and Engineering
Polymer Properties and Design
Materials Properties and Design
or any 3- or 4-credit lecture- or laboratory-based course (research and independent study courses are excluded) that is 300-level or higher, in an engineering or designated science department. Designated science departments are Chemistry; Physics; Biology; Biochemistry.
Engineering Elective: Any 3- or 4-credit lecture- or laboratory-based course (research and independent study courses are excluded) that is 200-level or higher, offered by the engineering school exclusive of the Department of Computer and Data Science *3
Total Units53

Technical Breadth Elective Sequences

A distinctive feature of the chemical engineering program is the three-course breadth elective sequence that enables a student to specialize in a technical or professional area that complements the chemical engineering core. Breadth elective sequences that have standing departmental approval are described below. Alternatively, students may design their own breadth elective sequence, which must be approved by the department.

Biochemical Engineering (Advisor: Dr. Baskaran)

BIOL 301Biotechnology Laboratory: Genes and Genetic Engineering3
BIOL 343Microbiology (Spring)3
ECHE 340Biochemical Engineering (Spring)3
Total Units9

Computing (Advisor: Dr. Lacks)

ECSE 281Logic Design and Computer Organization4
ECSE 346Engineering Optimization3
One additional EECS course at 200 level or above3-4
Total Units10-11

Electrochemical Engineering (Advisor: Dr. Landau)

ECHE 381Electrochemical Engineering (Spring)3
ECHE 383Chemical Engineering Applied to Microfabrication and Devices (Fall)3
One additional course selected from:3
Processing of Electronic Materials
ECSE 309Electromagnetic Fields I3
ECSE 321Semiconductor Electronic Devices4
Corrosion Fundamentals
Total Units16

Electronic Materials (Advisor: Dr. Liu)

ECHE 383Chemical Engineering Applied to Microfabrication and Devices (Fall)3
ECSE 309Electromagnetic Fields I3
One additional course selected from:3
Processing of Electronic Materials
Semiconductor Electronic Devices
Total Units9

Energy (Advisor: Dr. Savinell)

ECHE 381Electrochemical Engineering (Fall)3
Two additional courses selected from approved energy course in Engineering, Physics, Chemistry, Management, or Law6-7
Total Units9-10

Environmental Engineering (Advisor: Dr. Feke)

ECIV 368Environmental Engineering (Spring)3
Two additional courses selected from:6
Engineering Hydraulics and Hydrology
Water Resources Engineering (Fall)
Solid and Hazardous Waste Management (Spring)
Seminar in Environmental Studies (Fall)
Environmental Geology
Environmental Law
Hydrogeology
Introduction to Global Issues
Total Units9

Management/Entrepreneurship (Advisor: Dr. Savinell)

ACCT 100Introduction to Accounting for Non-Business Majors3
Two additional courses selected from:6
Corporate Finance (Fall)
Money and Banking
Legal Environment of Management
Entrepreneurial Strategy
Entrepreneurship and Wealth Creation
Operations Research and Supply Chain Management
International Management Institute
Total Units9

Polymer Science (Advisor: Dr. Akolkar)

EMAC 270Introduction to Polymer Science and Engineering (Fall)3
Two additional courses selected from:6
Polymer Properties and Design (Spring)
Polymer Engineering (Spring)
Polymer Processing (Spring)
Polymer Engineer Design Product (Spring)
Structure of Biological Materials
Total Units9

Pre-Medical (Advisor: Dr. Baskaran)

CHEM 113Principles of Chemistry Laboratory2
BIOL 214Genes, Evolution and Ecology3
BIOL 214LGenes, Evolution and Ecology Lab1
BIOL 215Cells and Proteins3
BIOL 215LCells and Proteins Laboratory1
Total Units10

Research (Advisor: Dr. Martin)

ECHE 350Undergraduate Research Project I (Fall)3
ECHE 351Undergraduate Research Project II3
An elective course approved by sequence advisor3
Total Units9

Systems and Control (Advisor: Dr. Lacks)

ECSE 281Logic Design and Computer Organization4
ECSE 304Control Engineering I with Laboratory3
ECSE 346Engineering Optimization3
Total Units10

BS/MS Advanced Study Sequence (Advisor: Dr. Martin)

Three 400-level 3-credit ECHE courses9
Total Units9

Custom-Designed Sequence (Advisor: Dr. Lacks)

Students can design a custom breadth elective sequence, consisting of three courses (9 credits) that fit in one coherent technical or professional theme. The courses must be technical or professional courses (see footnote a) that are 200-level or higher, with at least one of the courses being 300-level or higher. These courses cannot be research or independent study courses. Students interested in this option should submit a petition to their advisor naming and explaining the coherent theme, why this theme complements the chemical engineering core for him/her, and how the three courses fit into this theme. The petition must be approved by the faculty of the Department of Chemical and Biomolecular Engineering.

Bachelor of Science in Engineering

Suggested Program of Study: Major in Chemical Engineering

This program of study considers requirements for students who matriculated in Fall 2020.  Students who matriculated in Fall 2019 may choose to opt into these requirements and follow this program of study.  Students who matriculated prior to Fall 2019 can find their requirements and suggested program of study in the General Bulletin for the year they matriculated.  Note that ECHE 361, ECHE 364 and ECHE 398 are 3-credit courses before 2022, and become 4-credit courses in 2022 and thereafter.

The following is a suggested program of study. Current students should always consult their advisers and their individual graduation requirement plans as tracked in SIS.

First YearUnits
FallSpring
Principles of Chemistry for Engineers (CHEM 111)**4  
Calculus for Science and Engineering I (MATH 121)**,c
or Calculus I (MATH 123)
4  
Elementary Computer Programming (ENGR 131)3  
FSxx SAGES First Seminar*4  
Introduction to Chemical Engineering at Case (ECHE 151)1  
PHED (2 half semester courses)*0  
Chemistry of Materials (ENGR 145)**  4
Calculus for Science and Engineering II (MATH 122)**,c
or Calculus II (MATH 124)
  4
General Physics I - Mechanics (PHYS 121)  4
USxx SAGES University Seminar I *  3
PHED (2 half semester courses)*  0
Year Total: 16 15
 
Second YearUnits
FallSpring
Introductory Organic Chemistry I (CHEM 223)c
or Organic Chemistry I (CHEM 323)
3  
Calculus for Science and Engineering III (MATH 223)**,c
or Calculus III (MATH 227)
3  
Thermodynamics, Fluid Dynamics, Heat and Mass Transfer (ENGR 225)**4  
Introduction to Chemical Systems (ECHE 260)3  
USxx SAGES University Seminar II*3  
Elementary Differential Equations (MATH 224)**,c
or Differential Equations (MATH 228)
  3
Statistics for Experimenters (STAT 313)
or Basic Statistics for Engineering and Science (STAT 312)
  3
Thermodynamics of Chemical Systems (ECHE 363)  4
General Physics II - Electricity and Magnetism (PHYS 122)  4
Breadth elective**  3
Year Total: 16 17
 
Third YearUnits
FallSpring
Transport Phenomena for Chemical Systems (ECHE 360)4  
Process Control (ECHE 367)4  
Introduction to Circuits and Instrumentation (ENGR 210)**4  
Breadth elective**3  
Separation Processes (ECHE 361)  4
Chemical Reaction Processes (ECHE 364)  4
Measurements Laboratory (ECHE 365)  3
Chemical Laboratory Methods for Engineers (CHEM 290)  3
Professional Communication for Engineers (ENGR 398)**  1
Professional Communication for Engineers (ENGL 398)**  2
Year Total: 15 17
 
Fourth YearUnits
FallSpring
Chemical Engineering Laboratory (ECHE 362)4  
Process Analysis, Design and Safety (ECHE 398)4  
Technical breadth elective sequence Ie3  
Technical breadth elective sequence IIe3  
Breadth elective**3  
Chemical Engineering Design Project (ECHE 399)i  3
Engineering electivef  3
Science/Engineering electiveg  3
Technical breadth elective sequence III e  3
Breadth elective**  3
Year Total: 17 15
 
Total Units in Sequence:  128

Hours required for graduation: 128


Pre-Medical Option

By using the flexibility provided by science and technical electives in the curriculum, students are able to pursue courses that provide the background needed for medical school. Students choose the following electives to meet the course requirements of most medical schools.

Science/Engineering elective: CHEM 224 or CHEM 324
Chemistry labs: CHEM 113 and CHEM 233 and CHEM 234 instead of CHEM 290
Breadth Elective Sequence: Pre-Medical sequence (described above)
One extra course: BIOC 307

Co-op and Internship Programs

Opportunities are available for students to alternate studies with work in industry or government as a co-op student, which involves paid full-time employment over seven months (one semester and one summer). Students may work in one or two co-ops, beginning in the third year of study. Co-ops provide students the opportunity to gain valuable hands-on experience in their field by completing a significant engineering project while receiving professional mentoring. During a co-op placement, students do not pay tuition but maintain their full-time student status while earning a salary. Learn more at http://engineering.case.edu/coop/. Alternatively or additionally, students may obtain employment as summer interns.

Five-Year Combined BS/MS Program

Outstanding undergraduate students have the opportunity to obtain an MS degree, with a thesis, in one additional year of study beyond the BS degree. (Normally, it takes two years beyond the BS to earn an MS degree.) In this program, an undergraduate student can take up to nine hours of graduate credit that simultaneously satisfies undergraduate degree requirements. Typically, students in this program start their research leading to the MS thesis in the fall semester of the senior year. The BS degree is awarded at the completion of the senior year. Application for admission to the five-year BS/MS program is made after completion of five semesters of coursework. Minimum requirements are a 3.2 grade point average and the recommendation of the department.  Review the Office of Undergraduate Studies BS/MS program requirements here.

Six-Year Cooperative BS/MS Program

The cooperative bachelor’s/master’s program enables outstanding students who are enrolled in the cooperative education program to earn an MS in one year beyond the BS degree. Students complete six credits of a graduate project during the second co-op period and follow an Advanced Study elective sequence. Up to nine credits of graduate coursework can be used to satisfy both graduate and undergraduate requirements. At the end of the fifth year, the student receives the BS degree. Upon completion of an additional 15 credits of graduate work the following year, the student receives the MS degree (non-thesis). Application for admission to the six-year co-op BS/MS program is made during the second semester of the junior year (this semester is taken in the fall of the fourth year). Minimum requirements are a 3.2 grade point average, satisfactory performance in the previous co-op assignment, and the recommendation of the department.


Minor in Electrochemical Engineering

Electrochemical engineering focuses on fundamental studies and engineering design of widely used and critically important processes and equipment associated with reactions involving charge transfer. Students will gain expertise in the design of indispensable devices such as batteries and fuel-cells, and technologically important processes such as metal production and purification, semiconductor metallization, corrosion, electrodeposition, and biological separations. Students take five courses to complete the minor. The required courses are:

ECHE 381Electrochemical Engineering3
ECHE 384Corrosion Fundamentals3
Plus three courses selected from the following:
Electrochemical Energy Storage
Electrochemical Processes and Devices
Processing of Electronic Materials
Electromagnetic Fields I
Semiconductor Electronic Devices

Minor in Biomolecular Engineering

Biomolecular engineering focuses on the molecular length scale, and seeks to convert molecular-level knowledge of biological phenomena into useful biochemical and chemical products and processes that are derived from living cells or their components. Areas of application include: drug research and development, biosensors, and regenerative medicine applications. Students take five courses to complete the minor:

ECHE 340Biochemical Engineering3
ECHE 355Quantitative Molecular, Cellular and Tissue Bioengineering3
ECHE 386Protein Engineering3
Plus two courses selected from the following:
Genes, Evolution and Ecology
Microbiology
Introduction to Biochemistry: From Molecules To Medical Science
Introduction to Chemical Systems *
Thermodynamics of Chemical Systems *

Minor in Chemical Engineering

The minor in chemical engineering is for students majoring in other disciplines. A minimum of 17 hours in chemical engineering courses are required for the minor. The required courses are:

ENGR 225Thermodynamics, Fluid Dynamics, Heat and Mass Transfer4
ECHE 260Introduction to Chemical Systems3
ECHE 360Transport Phenomena for Chemical Systems4
Plus two courses selected from the following:6-7
Separation Processes
Thermodynamics of Chemical Systems
Chemical Reaction Processes
Measurements Laboratory
Process Control
Total Units17-18

Graduate Programs

Master of Science Program

Each MS candidate must complete a minimum of 30 hours of graduate-level credits. These credits can be distributed in one of three ways: Thesis-Focused, Project-Focused, or Course-Focused.

Thesis-Focused

ECHE 401Chemical Engineering Communications1
ECHE 402Chemical Engineering Communications II2
Six graduate-level courses a18
MS thesis research9
Total Units30

or

Project-Focused

ECHE 401Chemical Engineering Communications1
ECHE 402Chemical Engineering Communications II2
Eight graduate-level courses a24
Project and/or Special Problems b3
Total Units30

Course-Focused

The Course-Focused M.S. degree program requirements consist of the completion of 30 hours of approved coursework at the 400 level or higher, satisfactory completion of the culminating course-focused experience, i.e. passing the course ENGR 600 with requirements defined by the student's curricular program, and additional requirements as specified by the program.  Students should consult with their academic advisor and/or department to determine the detailed requirements within this framework.

Full-time MS students are expected to serve as a teaching assistant as part of their education. Also, at various points during their thesis research, students will be required to present seminars and reports on their progress.

Doctor of Philosophy Program

The degree of Doctor of Philosophy is awarded in recognition of deep and detailed knowledge of chemical engineering and a comprehensive understanding of related subjects together with a demonstration of the ability to perform independent research, to suggest new areas for research, and to communicate results in an acceptable manner. For students entering the PhD program with a BS degree, a total of 12 courses (36 credit hours) is required. Course requirements for students entering with MS degrees are adjusted to account for work done at other universities, but a minimum of 6 courses (18 credit hours) must be taken at CWRU. The course requirements for students entering with a BS degree are as follows:

Core and Elective courses a30
Professional Development courses b6
PhD thesis research c18
Total Units54

The department anticipates that from time to time, special cases will arise which are exceptions to the above guidelines, e.g., a student may have taken a graduate-level course at another school. In these cases, the student must submit a statement with the Academic Program justifying the departure from the guidelines and have it approved by the department.

Facilities

The department is housed in the Albert W. Smith Building and portions of the Bingham Building on the Case Quadrangle. Professor Smith was chair of industrial chemistry at Case from 1911 to 1927. Under his leadership a separate course of study in chemical engineering was introduced at Case in 1913. Professor Smith was also a close associate of Herbert Dow, the Case alumnus who founded Dow Chemical in 1890 with the help and support of Professor Smith. The Albert W. Smith Chemical Engineering Building contains one technology-enhanced classroom; the undergraduate Unit Operations Laboratory; an undergraduate reading room, named after Prof. Robert V. Edwards; and the normal complement of offices and research laboratories. The lobby of the A.W. Smith Building, renovated by contributions from the James family, often serves as a formal and informal gathering place for students and faculty. The department has exceptionally strong facilities for electrochemical and energy research, for microfabrication, and for chemical vapor deposition and thin film synthesis. In addition, a full range of biochemical, analytical and materials characterization instrumentation is available in the Case School of Engineering. Analytical instrumentation is available within the Department of Chemical and Biomolecular Engineering, the Department of Chemistry, and the Materials Research Laboratory.

Courses

ECHE 151. Introduction to Chemical Engineering at Case. 1 Unit.

An introduction to the profession of chemical engineering, its practice in industry, and review of the challenges and opportunities for the profession. The academic programs and curricular enhancements available to students majoring in chemical engineering at CWRU, including breadth sequence sequences and concentrations, undergraduate research, international study opportunities, cooperative education and internships, are presented. In addition to introducing the chemical engineering faculty and their research, a number of guest speakers representing the broad professional opportunities discuss career options with the students. Through lectures and discussions, students are also introduced to topics such as professionalism and ethics. Upperclassmen students conduct their co-op debriefing in the class, sharing experiences and initiating networking. In the lab/recitation section, students in smaller groups conduct experiments on chemical processes, spanning different aspects of the profession, and run computer-based simulations of those experiments. Analysis and discussion of the results will follow. Chemical engineering upperclassmen serve as teaching assistants.

ECHE 250. Honors Research I. 1 - 3 Units.

A special program which affords a limited number of students the opportunity to conduct research under the guidance of one of the faculty. At the end of the first semester of the sophomore year, students who have a strong interest in research are encouraged to discuss research possibilities with the faculty. Assignments are made based on mutual interest. Subject to the availability of funds, the faculty employs students through the summers of their sophomore and junior years, as members of their research teams.

ECHE 251. Honors Research II. 1 - 3 Units.

(See ECHE 250.) Recommended preparation: ECHE 250.

ECHE 260. Introduction to Chemical Systems. 3 Units.

Material and energy balances. Conservation principles and the elementary laws of physical chemistry applied to chemical processes. Developing skills in quantitative formulation and solution of word problems. Prereq: Sophomore Standing and (CHEM 111 OR CHEM 106). Prereq or Coreq: MATH 122 or MATH 124.

ECHE 305. Topics in Chemical Engineering. 1 - 3 Units.

Topics in chemical engineering will be covered in an independent study mode. Readings and homework assignments will be assigned. Students are graded on the basis of homework assignments and a final exam.

ECHE 340. Biochemical Engineering. 3 Units.

Chemical engineering principles applied to biological and biochemical systems and related processes. Microbiology and biochemistry linked with transport phenomena, kinetics, reactor design and analysis, and separations. Specific examples of microbial and enzyme processes of industrial significance. Recommended preparation: BIOC 307, BIOL 343 and ECHE 364, or permission of instructor.

ECHE 350. Undergraduate Research Project I. 3 Units.

This course affords a student the opportunity to conduct research under the guidance of one of the faculty, as part of the Chemical Engineering Research breadth elective sequence. Students who have a strong interest in research are encouraged to discuss research possibilities with the faculty. Assignments are made based on mutual interest.

ECHE 351. Undergraduate Research Project II. 3 Units.

This course affords a student the opportunity to conduct research under the guidance of one of the faculty, as part of the Chemical Engineering Research breadth elective sequence. Students who have a strong interest in research are encouraged to discuss research possibilities with the faculty. Assignments are made based on mutual interest. Prereq: ECHE 350.

ECHE 355. Quantitative Molecular, Cellular and Tissue Bioengineering. 3 Units.

Physical and chemical principles associated with kinetics and mass transport. Molecular-cellular components incorporated in quantitative analysis of cellular, tissue, and organ systems. Mathematical and computational modeling developed for diagnostic and therapeutic applications. Offered as EBME 350 and ECHE 355.

ECHE 360. Transport Phenomena for Chemical Systems. 4 Units.

Fundamentals of fluid flow, heat and mass transport from the microscopic and macroscopic perspectives. Applications to chemical systems, including steady and transient operations, convective and molecular (conduction and diffusion) effects, and interfacial transport. Design of unit operations (e.g., heat exchangers). Heat and mass transfer analogies. Vector/tensor analysis and dimensional analysis used throughout. Prereq: Junior Standing and (ENGR 225 or (Prereq or coreq: EMAC 352)) and (MATH 223 or MATH 227).

ECHE 361. Separation Processes. 4 Units.

Analysis and design of separation processes involving distillation, extraction, absorption, adsorption, and membrane processes. Design problems and the physical and chemical processes involved in separation. Equilibrium stage, degrees of freedom in design, graphical and analytical design techniques, efficiency and capacity of separation processes. Prereq: ECHE 260. Prereq or Coreq: ECHE 363.

ECHE 362. Chemical Engineering Laboratory. 4 Units.

Experiments in the operation of separation and reaction equipment, including design of experiments, technical analysis, and economic analysis. Experiments cover distillation, liquid-liquid extraction, heat transfer, fluidized beds, control, membrane separations, and chemical and electrochemical reactors. Prereq: ECHE 260, ECHE 360, ECHE 361, ECHE 363 and ECHE 364.

ECHE 362D. Chemical Engineering Laboratory in Denmark. 4 Units.

Chemical Engineering Laboratory in Denmark. A version of ECHE 362 taught during the summer at DTU in Lyngby. Prereq: ECHE 260 and ECHE 360 and ECHE 361 and ECHE 363 and ECHE 364.

ECHE 363. Thermodynamics of Chemical Systems. 4 Units.

First law, second law, phase equilibria, phase rule, chemical reaction equilibria, and applications to engineering problems. Thermodynamic properties of real substances, with emphasis on solutions. Thermodynamic analysis of processes including chemical reactions. Recommended preparation: ECHE 260. Prereq or Coreq: ENGR 225.

ECHE 364. Chemical Reaction Processes. 4 Units.

Design of homogeneous and heterogeneous chemical reactor systems. Relationships between type of reaction and choice of reactor. Methods of obtaining and analyzing kinetic data. Relationship between mechanism and reaction rate and brief introduction to catalysis. Recommended preparation: ECHE 360. Prereq: ECHE 260. Prereq or coreq: MATH 224 or MATH 228.

ECHE 365. Measurements Laboratory. 3 Units.

Laboratory introduction to the measurement process in engineering. Matching measurements to approximate and exact physical models is stressed. Extraction of physical parameters and estimation of the errors in the parameter estimates is an important part of the course. Example projects cover steady and unsteady state heat transfer, momentum transfer, and the first law of thermodynamics. Recommended preparation: ECHE 360. Prereq: ECHE 260 and ENGR 225. Prereq or Coreq: ECHE 363.

ECHE 367. Process Control. 4 Units.

Theoretical and practical aspects of feedback control of chemical processes. The course involves extensive use of computer software with some exams taken using the computer. Short laboratories and Labview training are integrated into the course. Topics include: analysis of linear dynamical systems using Laplace transforms, derivation of unsteady state mathematical models of simple chemical processes, dynamic simulation of linear and nonlinear models, design of PID controllers by model inverse methods, tuning of controller to accommodate process model uncertainty, two degrees of freedom controllers, feed-forward and cascade control. The Labview training covers programming basics, interfacing to a data acquisition system, and incorporating control algorithms.. Prereq or Coreq: (MATH 224 OR MATH 228) AND ECHE 260.

ECHE 372. Electrochemical Energy Storage. 3 Units.

Batteries and supercapacitors as part of renewable energy systems are introduced. Related fundamental electrochemistry concepts, materials and techniques are described. Challenges, current literature and future opportunities in energy storage will be discussed. Offered as ECHE 372 and ECHE 472. Prereq: Junior or Senior standing or Requisites Not Met permission.

ECHE 377. Data Acquisition and LabVIEW Bootcamp. 1 Unit.

This course will introduce and implement basic data acquisition concepts and LabVIEW virtual instrumentation programming, providing hands-on experience with hardware and software. It is intended to help those with little or no data acquisition experience to get started on setting up data acquisition for their application. No prior experience with LabVIEW is required. Consult with the instructor for additional details. Offered as ECHE 377 and ECHE 477.

ECHE 381. Electrochemical Engineering. 3 Units.

Engineering aspects of electrochemical processes including current and potential distribution, mass transport and fluid mechanical effects. Examples from industrial processes including electroplating, industrial electrolysis, corrosion, and batteries. Recommended preparation: ECHE 260 or permission of instructor. Offered as ECHE 381 and ECHE 480.

ECHE 382. Electrochemical Processes and Devices. 3 Units.

The course addresses major industrial applications of electrochemical technology focusing on batteries and fuel-cells, corrosion and its abatement, electroplating, metal electrowinning (including aluminum, magnesium, titanium and lithium) and refining (copper), industrial electrolytic processes (chlorine), electrochemical separation processes (electrophoresis, osmosis, and dialysis), and electrochemical sensors. The processes and devices are surveyed, focusing on the underlying thermodynamic and transport principles. Approaches to overcome barriers are discussed and future prospects and barriers are critically analyzed.

ECHE 383. Chemical Engineering Applied to Microfabrication and Devices. 3 Units.

Silicon based microfabrication and micromachining require many chemical engineering technologies. Microfabricated devices such as sensors are also directly related to chemical engineering. The applications of chemical engineering principles to microfabrication and micromachining are introduced. Oxidation processing, chemical vapor deposition, etching and patterning techniques, electroplating and other technologies are discussed. Graduate students will submit an additional final project on some technical aspect of microfabrication technology or devices. Recommended preparation: ECHE 363. Offered as ECHE 383 and ECHE 483.

ECHE 384. Corrosion Fundamentals. 3 Units.

This course will cover fundamentals of corrosion, including thermodynamic and kinetic aspects of the electrochemical reactions leading to corrosion. Salient features of the various types of corrosion will be reviewed, with an emphasis on fundamental mechanisms. Electrochemical testing, corrosion monitoring and techniques to stifle corrosion will be discussed. After completion of this course, students will be able to classify corrosion systems, understand the mechanisms underlying corrosion, and outline strategies to design corrosion-resistant systems. Offered as ECHE 384 and ECHE 481.

ECHE 386. Protein Engineering. 3 Units.

This course will provide an in-depth examination of protein engineering topics and their applications. In particular, this class will cover the design and expression of recombinant proteins, purification strategies, and the incorporation of non-natural amino acids using a bacterial system. Specifically, amino acid sequences that dictate well-defined secondary structures such as beta-sheets, alpha-helices, and leucine zippers will be studied. Tissue engineering examples from the literature such as incorporation of bioactive sequences to promote specific cell response (e.g., cell adhesion sites and protease degradation sequences). In addition, this course will explore the application of protein engineering in drug delivery, electrochemical technology, sensors, and nanoparticle assembly. Current computational techniques for protein design and directed evolution methods will also be explored. Offered as ECHE 386 and ECHE 486.

ECHE 398. Process Analysis, Design and Safety. 4 Units.

Economic analysis and cost estimation of chemical processes. Equipment and materials selection in the chemical process industry. Scale consideration, plant layout and plant site selection. Process analysis, heuristics and optimization. Environmental and plant safety issues. Prereq: ENGR 225 and ECHE 260 and ECHE 361 and ECHE 363 and ECHE 364. Prereq or Coreq: ECHE 360.

ECHE 399. Chemical Engineering Design Project. 3 Units.

Students work in small groups on projects in conjunction with external companies. The projects are defined by the company, and involve real issues current at the company. All projects will involve design (i.e., open ended problems with no one solution or route), an economic analysis, and will account for possible safety and environmental issues. The nature of the projects varies, depending on the needs of each company. There are no lectures for this course, and students are expected to work on their project for an amount appropriate for a 3-credit course (10 hrs/week). Recommended preparation: ECHE 362, ECHE 365, and ECHE 398. Counts as SAGES Senior Capstone. Prereq: ECHE 360, ECHE 361, ECHE 364, and ECHE 367.

ECHE 400T. Graduate Teaching I. 0 Unit.

All Ph.D. students are required to take this course. The experience includes elements from the following tasks: development of teaching or lecture materials, teaching recitation groups, providing laboratory assistance, tutoring, exam/quiz/homework preparation and grading, mentoring students. Recommended preparation: Entering Ph.D. student in Chemical Engineering.

ECHE 401. Chemical Engineering Communications. 1 Unit.

Introductory course in communication for Chemical Engineering graduate students: preparation of first proposal for thesis, preparation of technical reports and scientific papers, literature sources, reviewing proposals, and manuscripts for professional journals, and making effective technical presentations.

ECHE 402. Chemical Engineering Communications II. 2 Units.

This course is a continuation of ECHE 401 and is designed to develop skills in writing proposals for funding research projects. The federal requirements are reviewed for submitting proposals to the major granting agents including NSF, NIH and DoD. We will study strategies for developing fundable projects. Each student will submit a research proposal for a thesis project and do an oral presentation of the project.

ECHE 431. Design of Chemical Engineering Systems: Material Analysis. 3 Units.

Applying fundamental mass-balance related analysis to industrial separations processes (distillation, absorption, membranes; both plate and packed columns), reactors (CSTR, PFR), and process control (PID feedback controllers). Utilizing relevant thermodynamics theory including liquid-vapor and solid-liquid phase diagrams and azeotropes as needed for separations. Fundamental theory will be integrated in comprehensive design applications including economic analysis (equipment costing, net-present value and return on investment). Process simulation software will be used to introduce students to advanced design tools. Outcome goal will be to have the students learn to integrate fundamental knowledge from different chemical engineering topics to the comprehensive design of processes of industrial relevance. Prereq: Graduate student standing.

ECHE 432. Design of Chemical Engineering Systems: Energy Analysis. 3 Units.

Applying energy balance analysis to the design of comprehensive engineering processes. Fluid-flow fundamentals including mechanical energy balance and Bernoulli's equation, viscous flow in conduits and around submerged objects, Newton's law of viscosity and Navier-Stokes equation, among others, will be applied to the analysis and design of systems of industrial significance. Scaling analysis will elucidate critical process parameters. Thermodynamics first and second laws will be applied together with heat transfer models based on differential and integral analysis to the design of heat transfer systems including heat exchangers. Fluid-flow and heat transport analysis will be combined with economic considerations to analyze comprehensive problems and optimize designs. Emphasis will be placed on green and sustainable energy processes. An outcome goal of the course is to have the students develop skills of integrating fundamental knowledge from the fields of fluid flow, heat transfer, and engineering economics to the analysis and design of comprehensive systems of practical interest. Prereq: Graduate student standing.

ECHE 460. Thermodynamics of Chemical Systems. 3 Units.

Phase equilibria, phase rule, chemical reaction equilibria in homogeneous and heterogeneous systems, ideal and non-ideal behavior of fluids and solutions, thermodynamic analysis of closed and open chemical systems with applications. Recommended preparation: ECHE 363.

ECHE 461. Transport Phenomena. 3 Units.

Mechanisms of heat, mass, and momentum transport on both molecular and continuum basis. Generalized equations of transport. Techniques of solution for boundary value problems in systems of conduction, diffusion, and laminar flow. Boundary layer and turbulent systems. Recommended preparation: ECHE 360.

ECHE 462. Chemical Reaction Engineering. 3 Units.

Steady and unsteady state mathematical modeling of chemical reactors from conservation principles. Interrelation of reaction kinetics, mass and heat transfer, flow phenomena. Catalytic and chemical vapor deposition reactors. Determination of kinetic parameters. Includes catalytic and chemical vapor deposition reactors. Recommended preparation: ECHE 364.

ECHE 464. Surfaces and Adsorption. 3 Units.

Thermodynamics of interfaces, nature of interactions across phase boundaries, capillary wetting properties of adsorbed films, friction and lubrication, flotation, detergency, the surface of solids, relation of bulk to surface properties of materials, non-catalytic surface reactions. Recommended preparation: CHEM 335 or equivalent.

ECHE 466. Colloid Science. 3 Units.

Stochastic processes and interparticle forces in colloidal dispersions. DLVO theory, stability criteria, and coagulation kinetics. Electrokinetic phenomena. Applications to electrophoresis, filtration, floatation, sedimentation, and suspension rheology. Investigation of suspensions, emulsions, gels, and association colloids. Recommended preparation: CHEM 335.

ECHE 469. Chemical Engineering Seminar. 0 Unit.

Distinguished outside speakers present current research in various topics of chemical engineering science. Graduate students also present technical papers based on thesis research.

ECHE 470. Graduate Research Colloquium. .5 Unit.

Outside speakers present lectures on their current research. Various topics in the areas of chemical engineering science , basic and applied chemistry, bioengineering, material science, and applied mathematics are covered in the lectures. Graduate students also present technical papers based on their own research. Students are graded on the submission of one- page summary reports on any two lectures.

ECHE 472. Electrochemical Energy Storage. 3 Units.

Batteries and supercapacitors as part of renewable energy systems are introduced. Related fundamental electrochemistry concepts, materials and techniques are described. Challenges, current literature and future opportunities in energy storage will be discussed. Offered as ECHE 372 and ECHE 472. Prereq: Graduate standing or Requisites Not Met permission.

ECHE 474. Biotransport Processes. 3 Units.

Biomedical mass transport and chemical reaction processes. Basic mechanisms and mathematical models based on thermodynamics, mass and momentum conservation. Analytical and numerical methods to simulate in vivo processes as well as to develop diagnostic and therapeutic methods. Applications include transport across membranes, transport in blood, tumor processes, bioreactors, cell differentiation, chemotaxis, drug delivery systems, tissue engineering processes. Recommended preparation: EBME 350 or equivalent. Offered as EBME 474 and ECHE 474.

ECHE 475. Chemical Engineering Analysis. 3 Units.

Mathematical analysis of problems in transport processes, chemical kinetics, and control systems. Examines vector spaces and matrices and their relation to differential transforms, series techniques (Fourier, Bessel functions, Legendre polynomials). Recommended preparation: MATH 224.

ECHE 477. Data Acquisition and LabVIEW Bootcamp. 1 Unit.

This course will introduce and implement basic data acquisition concepts and LabVIEW virtual instrumentation programming, providing hands-on experience with hardware and software. It is intended to help those with little or no data acquisition experience to get started on setting up data acquisition for their application. No prior experience with LabVIEW is required. Consult with the instructor for additional details. Offered as ECHE 377 and ECHE 477.

ECHE 478. Membrane Separations. 3 Units.

Membrane-based separations provide a low-energy technique for performing chemical engineering separations and have applications in water treatment, energy, and human health. This course will provide an introduction to membrane transport mechanisms including solution diffusion, pore-flow and active transport. The course will also cover membrane fabrication methods, analytical techniques for membrane characterization and performance metrics. Fundamental concepts will be discussed in the context of particle filtration, nanofiltration, reverse osmosis, gas separations processes and emerging applications like membrane chromatography. Prereq: Graduate Standing or Requisites Not Met permission.

ECHE 479. Radiochemistry. 3 Units.

This course is intended to provide students with a basic understanding of fundamental chemical and physical properties of radioactive elements. The course will begin with a review of radioactive decay modes and nuclear chemistry. The majority of the course will focus on the solution chemistry, bonding, kinetics and thermodynamics of actinides in the context of analytical purification processes such as liquid-liquid extraction and resin-based chromatography. Common radioanalytical techniques such as gamma spectroscopy, alpha spectroscopy and liquid scintillation counting will also be discussed. Prereq: Graduate student standing.

ECHE 480. Electrochemical Engineering. 3 Units.

Engineering aspects of electrochemical processes including current and potential distribution, mass transport and fluid mechanical effects. Examples from industrial processes including electroplating, industrial electrolysis, corrosion, and batteries. Recommended preparation: ECHE 260 or permission of instructor. Offered as ECHE 381 and ECHE 480.

ECHE 481. Corrosion Fundamentals. 3 Units.

This course will cover fundamentals of corrosion, including thermodynamic and kinetic aspects of the electrochemical reactions leading to corrosion. Salient features of the various types of corrosion will be reviewed, with an emphasis on fundamental mechanisms. Electrochemical testing, corrosion monitoring and techniques to stifle corrosion will be discussed. After completion of this course, students will be able to classify corrosion systems, understand the mechanisms underlying corrosion, and outline strategies to design corrosion-resistant systems. Offered as ECHE 384 and ECHE 481.

ECHE 483. Chemical Engineering Applied to Microfabrication and Devices. 3 Units.

Silicon based microfabrication and micromachining require many chemical engineering technologies. Microfabricated devices such as sensors are also directly related to chemical engineering. The applications of chemical engineering principles to microfabrication and micromachining are introduced. Oxidation processing, chemical vapor deposition, etching and patterning techniques, electroplating and other technologies are discussed. Graduate students will submit an additional final project on some technical aspect of microfabrication technology or devices. Recommended preparation: ECHE 363. Offered as ECHE 383 and ECHE 483.

ECHE 486. Protein Engineering. 3 Units.

This course will provide an in-depth examination of protein engineering topics and their applications. In particular, this class will cover the design and expression of recombinant proteins, purification strategies, and the incorporation of non-natural amino acids using a bacterial system. Specifically, amino acid sequences that dictate well-defined secondary structures such as beta-sheets, alpha-helices, and leucine zippers will be studied. Tissue engineering examples from the literature such as incorporation of bioactive sequences to promote specific cell response (e.g., cell adhesion sites and protease degradation sequences). In addition, this course will explore the application of protein engineering in drug delivery, electrochemical technology, sensors, and nanoparticle assembly. Current computational techniques for protein design and directed evolution methods will also be explored. Offered as ECHE 386 and ECHE 486. Prereq: Graduate standing or requisites not met permission.

ECHE 500T. Graduate Teaching II. 0 Unit.

All Ph.D. students are required to take this course. The experience will include elements from the following tasks: development of teaching or lecture materials, teaching recitation groups, providing laboratory assistance, tutoring, exam/quiz/homework preparation and grading, mentoring students. Recommended preparation: Ph.D. student in Chemical Engineering.

ECHE 508. Seminar on Review of Literature on Research Topic. 3 Units.

Impactful research requires a deep and comprehensive understanding of the current state of research on the topic. A critical review of relevant background literature will help determine what is already known on the topic, how extensively the topic has already been studied, who are the experts active in the field, and the relevant key questions that deserve further exploration. A review of the literature that describes methodologies (both experimental and theoretical) used in prior studies or new approaches that could be adapted from other research areas can also lead to the effective pursuit of the research topic. Through this course, students will learn how to develop a plan for a literature review, conduct the literature review and monitor continuing developments in the field, and create an annotated bibliography appropriate to the research project.

ECHE 509. Seminar on Preparation of Articles for Publication in Journals. 3 Units.

This course is intended for advanced graduate students who have generated results at the stage of being ready to be written up for a journal article. The course will cover: understanding what findings warrant publication, factors affecting journal selection, formatting requirements of journals, publication-quality figures, appropriate material for each of the sections of the paper. During the course students will be putting together a manuscript based on their research that would eventually be submitted to a journal.

ECHE 580. Special Topics. 3 Units.

Special topics in chemical engineering. Prereq: Consent of instructor.

ECHE 600T. Graduate Teaching III. 0 Unit.

All Ph.D. students are required to take this course. The experience will include elements from the following tasks: development of teaching or lecture materials, teaching recitation groups, providing laboratory assistance, tutoring, exam/quiz/homework preparation and grading, mentoring students. Recommended preparation: Ph.D. student in Chemical Engineering.

ECHE 601. Independent Study. 1 - 18 Units.


ECHE 651. Thesis M.S.. 1 - 18 Units.

(Credit as arranged.)

ECHE 660. Special Problems. 1 - 18 Units.

Research course taken by Plan B M.S. students.

ECHE 695. Project M.S.. 1 - 9 Units.

Research course taken by Plan B M.S. students. Prereq: Enrolled in ECHE Plan B Program.

ECHE 701. Dissertation Ph.D.. 1 - 9 Units.

(Credit as arranged.) Prereq: Predoctoral research consent or advanced to Ph.D. candidacy milestone.